Hawaii Macula and Retina Institute Clinical Trials

Treatment options for wet-AMD and diabetic retinopathy are still being researched and studied.  Lucentis and Avastin have revolutionized the treatment of wet-AMD and Diabetic Retinopathy and prior to 2006, the medication was only available through clinical trials.  In Hawaii, these medications were available as early as 2002 through our research center (almost 4 years before it became FDA approved) through various clinical trials.  Sometimes, research trials can provide additional treatment options, research is not an option for everyone so please talk to your doctors if you feel that you might be a candidate for a clinical trial.  All research conducted at our clinic is reviewed by an Institutional Review Board as required by the FDA.

Open Enrolling Trials

  • SAPPHIRE-Evaluation of Suprachoroidal CLS-TA in Conjunction with Intravitreal Aflibercept in Patients with Retinal Vein Occlusions (Primary Investigator: James C. Lai, MD)
  • OPH2006 – Evaluates the safety and efficacy of Zimura in combination with aflibercept in patients with polypoidal choroidal vasculopathy (Primary Investigator: Gregg T. Kokame, MD)

Ongoing Trials

Completed Trials