Hawaii Macula and Retina Institute Clinical Trials

Treatment options for wet-AMD and diabetic retinopathy are still being researched and studied.  Lucentis and Avastin have revolutionized the treatment of wet-AMD and Diabetic Retinopathy and prior to 2006, the medication was only available through clinical trials.  In Hawaii, these medications were available as early as 2002 through our research center (almost 4 years before it became FDA approved) through various clinical trials.  Sometimes, research trials can provide additional treatment options, research is not an option for everyone so please talk to your doctors if you feel that you might be a candidate for a clinical trial.  All research conducted at our clinic is reviewed by an Institutional Review Board as required by the FDA.

Open Enrolling Trials

  • YOSEMITE—Investigates the safety and efficacy of faricimab in patients with diabetic macular edema
  • MERLIN—Investigates the safety and efficacy of brolucizumab 6mg every 4 weeks in patients with wet AMD with persistent retinal fluid
  • KESTREL—Investigates the safety and efficacy of brolucizumab versus aflibercept in patients with visual impairment due to diabetic macular edema
  • PANDA—Investigates the efficacy and safety of conbercept intravitreal injection in patients with treatment naïve wet AMD
  • SALUTARIS—Investigates the safety of the SMD-DA to deliver radiation therapy to treatment naïve wet AMD /
    Polypoidal choroidal vasculopathy

Completed Trials